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  • Tolerability - Wikipedia
    Tolerability of a particular drug can be discussed in a general sense, or it can be a quantifiable measurement as part of a clinical study Usually, it is measured by the rate of "dropouts", or patients that forfeit participation in a study due to extreme adverse effects
  • Defining Patient Tolerability to Cancer Treatments Helps Reduce . . .
    Assessing the toxicity and tolerability of cancer treatments from the patient’s perspective is critical: Patients who experience side effects from cancer therapies may not finish their treatment, missing a chance for treatment success
  • BROADENING THE DEFINITION OF TOLERABILITY IN CANCER CLINICAL TRIALS TO . . .
    The tolerability of a medical product is the degree to which symptomatic and non-symptom-atic adverse events associated with the product’s administration afect the ability or desire of the patient to adhere to the dose or intensity of therapy
  • Drug tolerability: How much ambiguity can be tolerated? A . . . - PubMed
    Aims: Drug tolerability refers to the degree to which drugs' overt adverse effects can be tolerated by patients The tolerability profile is of comparative importance to its efficacy and safety, as it largely determines adherence to treatment and ultimately treatment success or failure
  • Safety Versus Tolerability - Clinical Therapeutics
    What is tolerable may depend upon whether the study participants are healthy volunteers or patients Tolerability is distinct from a clinically significant change in a vital sign or a laboratory test that could be an indicator of lack of safety
  • tolerability - The Multi-Regional Clinical Trials Center of Brigham and . . .
    How much a participant or group of participants can accept a study treatment's unwanted effects so they can keep taking it Many drug studies look at the tolerability of the study treatment Tolerability is looked at to find out how easy it is for treatment to be delivered
  • TOLERABLE Definition Meaning - Merriam-Webster
    The meaning of TOLERABLE is capable of being borne or endured How to use tolerable in a sentence
  • Tolerability - definition of tolerability by The Free Dictionary
    Define tolerability tolerability synonyms, tolerability pronunciation, tolerability translation, English dictionary definition of tolerability adj 1 Capable of being tolerated; endurable: found the workload tolerable and so kept the job
  • Drug Tolerability - an overview | ScienceDirect Topics
    Drug tolerability is defined as the degree to which patients can tolerate a medication without experiencing significant adverse events, typically measured by comparing the rates of treatment discontinuation due to side effects between the active drug and placebo in clinical trials
  • Measuring the multidimensional aspects of tolerability
    As new cancer therapies emerge and evolve, there is a need for a better understanding of their safety and tolerability Safety and tolerability are distinct, albeit related, constructs; an unsafe treatment cannot be considered tolerable, whereas safe treatments may not be tolerable to some patients





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